Enrichment graph

You can view the Enrichment graph for a completed group analysis.

Here you can functionally characterize proteins showing abundance difference between groups compared by performing gene ontology (GO) enrichment.

Enrichment plot, shown as an ontology plot (hierarchical tree)

  1. Select to condense similar terms by family.

  2. Select to display the plot as either a Dot Plot or Ontology Plot.

  3. Select to switch between GO categories.

How to open and use

  • To open after running a group analysis , select Enrichment on the Group Analysis toolbar.

  • Use the list to switch between GO categories: Molecular Function, Biological Process, and Cellular Compartment.

  • To set the cutoff (adjusted p-value upper limit), select  Chart Settings on the graph.

  • Display the GO term enrichment as either:

    • Dot Plot button Dot Plot — To “condense” similar terms by family (i.e., condense all children from each superfamily), select the Summarize Terms checkbox.

    • Ontology Plot button Ontology Plot (hierarchical tree)

      • Hover over a box to view GO information.

      • Use the mouse wheel to zoom into and out of the plot.

      • Drag the plot to reposition it so that you can examine different areas.